Wound Care8 min read

Arterial Ulcers vs. Venous Ulcers: Know the Difference

Understanding whether your leg ulcer is arterial or venous is critical—they require completely different treatments.

Leg ulcers may look similar, but arterial and venous ulcers have very different causes and require opposite treatment approaches. Getting the diagnosis right is the first step to healing.

Side-by-Side Comparison

Feature Arterial Ulcers Venous Ulcers
Cause Blocked arteries (poor blood flow TO the leg) Faulty vein valves (poor blood flow FROM the leg)
Location Toes, heels, bony areas of feet Inner ankle, lower leg
Appearance Deep, "punched out" look with pale/gray base Shallow, irregular edges, red base
Pain Severe, worse with elevation Aching, improves with elevation
Leg Temperature Cool or cold Normal or warm
Pulses Weak or absent Normal
Key Treatment Restore blood flow (revascularization) Compression therapy

Critical Warning

Never apply compression to an arterial ulcer! Compression can cut off remaining blood supply and cause tissue death. This is why proper diagnosis is essential before starting treatment.

Treatment Differences

Arterial Ulcer Treatment

  • • Vascular assessment (ABI, angiogram)
  • • Revascularization (angioplasty, stent, bypass)
  • • Gentle wound care—no compression
  • • Smoking cessation critical
  • • Control diabetes and cholesterol

Venous Ulcer Treatment

  • • Compression therapy (stockings, wraps)
  • • Leg elevation
  • • Wound care and dressings
  • • Consider vein procedures (ablation)
  • • Lifelong compression for prevention

Mixed Ulcers

Some patients have both arterial and venous disease, creating "mixed" ulcers. These require careful evaluation to determine the safest treatment approach—often modified compression with close monitoring.

Not Sure What Type of Ulcer You Have?

Our vascular specialists can diagnose your ulcer and create the right treatment plan.